Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM403693
Substrate
n/a
Meas. Tech.
GPR120 pERK AlphaScreen SureFire Assay
EC50
750±n/a nM
Citation
 Cheng, PT; Yoon, DS Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators US Patent  US10336684 Publication Date 7/2/2019 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM403693
Synonyms:
2-(4-(3-Phenoxycycloheptyl)phenethoxy)acetic acid (diastereomeric mixture) | US10336684, Example 14 | US10336684, Example 15 | US10336684, Example 16 | US10336684, Example 17
Type:
Small organic molecule
Emp. Form.:
C23H28O4
Mol. Mass.:
368.466
SMILES:
OC(=O)COCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Structure:
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