Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM403704
Substrate
n/a
Meas. Tech.
GPR120 pERK AlphaScreen SureFire Assay
EC50
540±n/a nM
Citation
 Cheng, PT; Yoon, DS Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators US Patent  US10336684 Publication Date 7/2/2019 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM403704
Synonyms:
(S)-5-(2,6-Difluoro-4-(3-phenoxypiperidin-1-yl)phenyl)pentanoic acid | US10336684, Example 25
Type:
Small organic molecule
Emp. Form.:
C22H25F2NO3
Mol. Mass.:
389.4356
SMILES:
OC(=O)CCCCc1c(F)cc(cc1F)N1CCC[C@@H](C1)Oc1ccccc1 |r|
Structure:
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