Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37610
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
IC50
>66700±n/a nM
Comments
Extracted from aid = 520 and tid = 3
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37610
Synonyms:
2-(3-ethoxy-4-hydroxyphenyl)-4-hydroxy-3-(5-methylfuran-2-carbonyl)-1-(2-phenylethyl)-2H-pyrrol-5-one | 2-(3-ethoxy-4-hydroxyphenyl)-4-hydroxy-3-[(5-methyl-2-furanyl)-oxomethyl]-1-(2-phenylethyl)-2H-pyrrol-5-one | 2-(3-ethoxy-4-oxidanyl-phenyl)-3-(5-methylfuran-2-yl)carbonyl-4-oxidanyl-1-(2-phenylethyl)-2H-pyrrol-5-one | 5-(3-Ethoxy-4-hydroxy-phenyl)-3-hydroxy-4-(5-methyl-furan-2-carbonyl)-1-phenethyl-1,5-dihydro-pyrrol-2-one | 5-(3-ethoxy-4-hydroxy-phenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-phenethyl-3-pyrrolin-2-one | MLS000033795 | SMR000013498 | cid_649540
Type:
Small organic molecule
Emp. Form.:
C26H25NO6
Mol. Mass.:
447.4798
SMILES:
CCOc1cc(ccc1O)C1C(C(=O)c2ccc(C)o2)C(=O)C(=O)N1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: