Reaction Details Report a problem with these data
Target
Cathepsin B
Ligand
BDBM37858
Substrate
n/a
Meas. Tech.
Cathepsin B Inhibitor Series SAR Study
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B Inhibitor Series SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM37858
Synonyms:
2-cyano-N'-(4-methylphenyl)sulfonyl-ethanehydrazide | 2-cyano-N'-(4-methylphenyl)sulfonylacetohydrazide | 2-cyano-N'-tosyl-acetohydrazide | PC-0094937 | PCMD-CC-MCM-20 | cid_5035758
Type:
Small organic molecule
Emp. Form.:
C10H11N3O3S
Mol. Mass.:
253.278
SMILES:
Cc1ccc(cc1)S(=O)(=O)NNC(=O)CC#N
Structure:
Search PDB for entries with ligand similarity: