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Target
cAMP-dependent protein kinase catalytic subunit alpha
Ligand
BDBM37869
Substrate
n/a
Meas. Tech.
Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity
IC50
>59640±n/a nM
Citation
 PubChem, PC Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity PubChem Bioassay (2007)[AID] 
Target
Name:
cAMP-dependent protein kinase catalytic subunit alpha
Synonyms:
KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit
Type:
Enzyme Catalytic Subunit
Mol. Mass.:
40598.73
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
  
Inhibitor
Name:
BDBM37869
Synonyms:
1-(2,3-Dihydro-indol-1-yl)-2-(5-pyridin-4-yl-tetrazol-2-yl)-ethanone | 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-1,2,3,4-tetrazol-2-yl)ethanone | 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yl-2-tetrazolyl)ethanone | 1-(2,3-dihydroindol-1-yl)-2-(5-pyridin-4-yltetrazol-2-yl)ethanone | 1-indolin-1-yl-2-[5-(4-pyridyl)tetrazol-2-yl]ethanone | MLS000073457 | SMR000003446 | cid_645070
Type:
Small organic molecule
Emp. Form.:
C16H14N6O
Mol. Mass.:
306.322
SMILES:
O=C(Cn1nnc(n1)-c1ccncc1)N1CCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: