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Target
cAMP-dependent protein kinase catalytic subunit alpha
Ligand
BDBM36919
Substrate
n/a
Meas. Tech.
Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity
IC50
16240±n/a nM
Citation
 PubChem, PC Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity PubChem Bioassay (2007)[AID] 
Target
Name:
cAMP-dependent protein kinase catalytic subunit alpha
Synonyms:
KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit
Type:
Enzyme Catalytic Subunit
Mol. Mass.:
40598.73
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
  
Inhibitor
Name:
BDBM36919
Synonyms:
2-[(4-chlorobenzyl)thio]-5-(4-pyridyl)-1,3,4-oxadiazole | 2-[(4-chlorophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole | 2-[(4-chlorophenyl)methylthio]-5-pyridin-4-yl-1,3,4-oxadiazole | MLS000080368 | SMR000035937 | cid_662339
Type:
Small organic molecule
Emp. Form.:
C14H10ClN3OS
Mol. Mass.:
303.767
SMILES:
Clc1ccc(CSc2nnc(o2)-c2ccncc2)cc1
Structure:
Search PDB for entries with ligand similarity: