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Target
cAMP-dependent protein kinase catalytic subunit alpha
Ligand
BDBM37899
Substrate
n/a
Meas. Tech.
Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity
IC50
>59640±n/a nM
Citation
 PubChem, PC Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity PubChem Bioassay (2007)[AID] 
Target
Name:
cAMP-dependent protein kinase catalytic subunit alpha
Synonyms:
KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit
Type:
Enzyme Catalytic Subunit
Mol. Mass.:
40598.73
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
  
Inhibitor
Name:
BDBM37899
Synonyms:
MLS000086255 | N-(1,3-benzodioxol-5-yl)-2-(1-keto-3-methyl-2-isoquinolyl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxidanylidene-isoquinolin-2-yl)ethanamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxo-2-isoquinolinyl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxoisoquinolin-2-yl)acetamide | N-1,3-benzodioxol-5-yl-2-(3-methyl-1-oxoisoquinolin-2(1H)-yl)acetamide | SMR000021764 | cid_3236683
Type:
Small organic molecule
Emp. Form.:
C19H16N2O4
Mol. Mass.:
336.3413
SMILES:
Cc1cc2ccccc2c(=O)n1CC(=O)Nc1ccc2OCOc2c1
Structure:
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