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Target
cAMP-dependent protein kinase catalytic subunit alpha
Ligand
BDBM37907
Substrate
n/a
Meas. Tech.
Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity
IC50
10990±n/a nM
Citation
 PubChem, PC Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity PubChem Bioassay (2007)[AID] 
Target
Name:
cAMP-dependent protein kinase catalytic subunit alpha
Synonyms:
KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit
Type:
Enzyme Catalytic Subunit
Mol. Mass.:
40598.73
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
  
Inhibitor
Name:
BDBM37907
Synonyms:
4-(4-methoxyphenyl)-6-(4-morpholinyl)-2H-pyrazolo[3,4-d]pyrimidin-3-amine | 4-(4-methoxyphenyl)-6-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-3-amine | 4-(4-methoxyphenyl)-6-morpholin-4-yl-2H-pyrazolo[3,4-d]pyrimidin-3-amine | MLS000044622 | SMR000022566 | [4-(4-methoxyphenyl)-6-morpholino-2H-pyrazolo[3,4-d]pyrimidin-3-yl]amine | cid_3244716
Type:
Small organic molecule
Emp. Form.:
C16H18N6O2
Mol. Mass.:
326.3531
SMILES:
COc1ccc(cc1)-c1nc(nc2n[nH]c(N)c12)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: