Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM38402
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
11160.8±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM38402
Synonyms:
1-[4-(2-furanyl)-6-(trifluoromethyl)-2-pyrimidinyl]benzotriazole | 1-[4-(2-furyl)-6-(trifluoromethyl)pyrimidin-2-yl]-1H-1,2,3-benzotriazole | 1-[4-(2-furyl)-6-(trifluoromethyl)pyrimidin-2-yl]benzotriazole | 1-[4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]benzotriazole | MLS000087475 | SMR000023698 | cid_3238760
Type:
Small organic molecule
Emp. Form.:
C15H8F3N5O
Mol. Mass.:
331.2521
SMILES:
FC(F)(F)c1cc(nc(n1)-n1nnc2ccccc12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: