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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35394
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35394
Synonyms:
6-chloranyl-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-7-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide | 6-chloro-N-(2-cyclohex-1-en-1-ylethyl)-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide | 6-chloro-N-[2-(1-cyclohexenyl)ethyl]-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide | 6-chloro-N-[2-(cyclohexen-1-yl)ethyl]-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide | 6-chloro-N-[2-(cyclohexen-1-yl)ethyl]-7-keto-5-methyl-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide | MLS000046070 | SMR000031679 | cid_3240744
Type:
Small organic molecule
Emp. Form.:
C16H19ClN4O2
Mol. Mass.:
334.801
SMILES:
Cc1nc2c(c[nH]n2c(=O)c1Cl)C(=O)NCCC1=CCCCC1 |t:19|
Structure:
Search PDB for entries with ligand similarity: