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Target
Mevalonate kinase
Ligand
BDBM38613
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
43485.3±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38613
Synonyms:
6-(methoxymethyl)-4-methyl-2-sulfanylidene-1H-pyridine-3-carbonitrile | 6-(methoxymethyl)-4-methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile | 6-(methoxymethyl)-4-methyl-2-thioxo-1H-pyridine-3-carbonitrile | MLS000085657 | SMR000020786 | cid_684366
Type:
Small organic molecule
Emp. Form.:
C9H10N2OS
Mol. Mass.:
194.254
SMILES:
COCc1cc(C)c(C#N)c(=S)[nH]1
Structure:
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