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Target
Mevalonate kinase
Ligand
BDBM38666
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38666
Synonyms:
5-cyclopropyl-N-(5-methyl-1,2-oxazol-3-yl)-1,2-oxazole-3-carboxamide | 5-cyclopropyl-N-(5-methyl-3-isoxazolyl)-3-isoxazolecarboxamide | 5-cyclopropyl-N-(5-methylisoxazol-3-yl)isoxazole-3-carboxamide | MLS000116344 | SMR000093321 | cid_5308020
Type:
Small organic molecule
Emp. Form.:
C11H11N3O3
Mol. Mass.:
233.2233
SMILES:
Cc1cc(NC(=O)c2cc(on2)C2CC2)no1
Structure:
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