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Target
Mevalonate kinase
Ligand
BDBM38611
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38611
Synonyms:
4-ethyl-3-(2-methylpropyl)-1H-1,2,4-triazole-5-thione | 4-ethyl-3-isobutyl-1H-1,2,4-triazole-5-thione | 4-ethyl-5-isobutyl-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000042976 | SMR000019403 | cid_3242936
Type:
Small organic molecule
Emp. Form.:
C8H15N3S
Mol. Mass.:
185.29
SMILES:
CCn1c(CC(C)C)n[nH]c1=S
Structure:
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