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Target
Dual specificity protein phosphatase 1
Ligand
BDBM35402
Substrate
n/a
Meas. Tech.
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of DTT
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of DTT PubChem Bioassay (2006)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM35402
Synonyms:
MLS000093276 | N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a]quinoxalin-4-amine | SMR000028898 | [2-morpholino-5-(trifluoromethyl)phenyl]-([1,2,4]triazolo[4,3-a]quinoxalin-4-yl)amine | cid_3242631
Type:
Small organic molecule
Emp. Form.:
C20H17F3N6O
Mol. Mass.:
414.3838
SMILES:
FC(F)(F)c1ccc(N2CCOCC2)c(Nc2nc3ccccc3n3cnnc23)c1
Structure:
Search PDB for entries with ligand similarity: