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Target
Dual specificity protein phosphatase 1
Ligand
BDBM35426
Substrate
n/a
Meas. Tech.
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
IC50
36681±n/a nM
Citation
 PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2006)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM35426
Synonyms:
5-({4-[2-cyano-2-(4-fluorophenyl)vinyl]-2-ethoxyphenoxy}methyl)-2-furoic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-ethoxy-phenoxy]methyl]furan-2-carboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-ethoxyphenoxy]methyl]-2-furancarboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)ethenyl]-2-ethoxyphenoxy]methyl]furan-2-carboxylic acid | 5-[[4-[(E)-2-cyano-2-(4-fluorophenyl)vinyl]-2-ethoxy-phenoxy]methyl]-2-furoic acid | MLS000051448 | SMR000079789 | cid_2224422
Type:
Small organic molecule
Emp. Form.:
C23H18FNO5
Mol. Mass.:
407.3911
SMILES:
CCOc1cc(\C=C(\C#N)c2ccc(F)cc2)ccc1OCc1ccc(o1)C(O)=O
Structure:
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