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Target
Dual specificity protein phosphatase 6
Ligand
BDBM31700
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase PubChem Bioassay (2006)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM31700
Synonyms:
(5Z)-5-(5-bromo-2-methoxybenzylidene)-2-(2-furyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one | 5-(5-bromo-2-methoxy-benzylidene)-2-(2-furyl)thiazolo[3,2-b][1,2,4]triazol-6-one | 5-[(5-bromanyl-2-methoxy-phenyl)methylidene]-2-(furan-2-yl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one | 5-[(5-bromo-2-methoxyphenyl)methylidene]-2-(2-furanyl)-6-thiazolo[3,2-b][1,2,4]triazolone | 5-[(5-bromo-2-methoxyphenyl)methylidene]-2-(furan-2-yl)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one | MLS000043560 | SMR000020576 | cid_3236807
Type:
Small organic molecule
Emp. Form.:
C16H10BrN3O3S
Mol. Mass.:
404.238
SMILES:
COc1ccc(Br)cc1C=c1sc2nc(nn2c1=O)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: