Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM38824
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38824
Synonyms:
1-(4-methoxybenzyl)-N-(3-morpholin-4-ylpropyl)-5-oxopyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-(3-morpholin-4-ylpropyl)-5-oxidanylidene-pyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-(3-morpholin-4-ylpropyl)-5-oxopyrrolidine-3-carboxamide | 1-[(4-methoxyphenyl)methyl]-N-[3-(4-morpholinyl)propyl]-5-oxo-3-pyrrolidinecarboxamide | 5-keto-N-(3-morpholinopropyl)-1-p-anisyl-pyrrolidine-3-carboxamide | MLS000046454 | SMR000032465 | cid_3242857
Type:
Small organic molecule
Emp. Form.:
C20H29N3O4
Mol. Mass.:
375.462
SMILES:
COc1ccc(CN2CC(CC2=O)C(=O)NCCCN2CCOCC2)cc1
Structure:
Search PDB for entries with ligand similarity: