Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 1
Ligand
BDBM31755
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison.
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM31755
Synonyms:
3-(benzylthio)-5,6-bis(2-furyl)-1,2,4-triazine | 3-benzylsulfanyl-5,6-bis(furan-2-yl)-1,2,4-triazine | 5,6-bis(2-furanyl)-3-(phenylmethylthio)-1,2,4-triazine | 5,6-bis(furan-2-yl)-3-(phenylmethylsulfanyl)-1,2,4-triazine | MLS-0029114.0001 | cid_2940938
Type:
Small organic molecule
Emp. Form.:
C18H13N3O2S
Mol. Mass.:
335.38
SMILES:
C(Sc1nnc(-c2ccco2)c(n1)-c1ccco1)c1ccccc1
Structure:
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