Reaction Details Report a problem with these data
Target
Coagulation factor XI
Ligand
BDBM32667
Substrate
n/a
Meas. Tech.
Factor XIa Dose Response Confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Factor XIa Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Coagulation factor XI
Synonyms:
Coagulation factor XIa | Coagulation factor XIa heavy chain | Coagulation factor XIa light chain | F11 | FA11_HUMAN | FXI | Factor XIa | Factor XIa (fXIa) | PTA | Plasma thromboplastin antecedent
Type:
Enzyme
Mol. Mass.:
70130.58
Organism:
Homo sapiens (Human)
Description:
P03951
Residue:
625
Sequence:
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
  
Inhibitor
Name:
BDBM32667
Synonyms:
3-furancarboxylic acid [2-(2-furanyl)-4-(phenyliminomethyl)-5-oxazolyl] ester | MLS000027589 | SMR000040036 | [2-(furan-2-yl)-4-(phenyliminomethyl)-1,3-oxazol-5-yl] furan-3-carboxylate | cid_659095 | furan-3-carboxylic acid [2-(2-furyl)-4-(phenyliminomethyl)oxazol-5-yl] ester
Type:
Small organic molecule
Emp. Form.:
C19H12N2O5
Mol. Mass.:
348.309
SMILES:
O=C(Oc1oc(nc1\C=N\c1ccccc1)-c1ccco1)c1ccoc1
Structure:
Search PDB for entries with ligand similarity: