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Target
Beta-lactamase
Ligand
BDBM39832
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7±0
Ki
5.5e+3±n/a nM
Citation
 Tondi, D; Powers, RA; Caselli, E; Negri, MC; Blázquez, J; Costi, MP; Shoichet, BK Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase. Chem Biol 8:593-611 (2001) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM39832
Synonyms:
Amide and sulfonamide derivatives, 16
Type:
Small organic molecule
Emp. Form.:
C8H13BN2O4S
Mol. Mass.:
244.076
SMILES:
CN(C)S(=O)(=O)Nc1cccc(c1)B(O)O
Structure:
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