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Target
14-3-3 protein gamma
Ligand
BDBM39865
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39865
Synonyms:
1-(4-morpholinyl)-3-(N-phenylanilino)-2-propanol;hydrochloride | 1-(diphenylamino)-3-morpholin-4-yl-propan-2-ol;hydrochloride | 1-morpholin-4-yl-3-(N-phenylanilino)propan-2-ol;hydrochloride | 1-morpholino-3-(N-phenylanilino)propan-2-ol;hydrochloride | MLS000037915 | SMR000057753 | cid_2836178
Type:
Small organic molecule
Emp. Form.:
C19H24N2O2
Mol. Mass.:
312.4061
SMILES:
OC(CN(c1ccccc1)c1ccccc1)CN1CCOCC1
Structure:
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