Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40508
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
9999000±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40508
Synonyms:
MLS000047251 | N-[4-(5-thien-2-yl-1,2,4-oxadiazol-3-yl)phenyl]nicotinamide | N-[4-(5-thiophen-2-yl-1,2,4-oxadiazol-3-yl)phenyl]-3-pyridinecarboxamide | N-[4-(5-thiophen-2-yl-1,2,4-oxadiazol-3-yl)phenyl]pyridine-3-carboxamide | N-[4-[5-(2-thienyl)-1,2,4-oxadiazol-3-yl]phenyl]nicotinamide | SMR000033262 | cid_3240032
Type:
Small organic molecule
Emp. Form.:
C18H12N4O2S
Mol. Mass.:
348.378
SMILES:
O=C(Nc1ccc(cc1)-c1noc(n1)-c1cccs1)c1cccnc1
Structure:
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