Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40514
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
13378.29±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40514
Synonyms:
MLS000043695 | N-(2-aminocarbonyl-1-benzofuran-3-yl)-1,3-benzothiazole-2-carboxamide | N-(2-carbamoyl-1-benzofuran-3-yl)-1,3-benzothiazole-2-carboxamide | N-(2-carbamoyl-3-benzofuranyl)-1,3-benzothiazole-2-carboxamide | N-(2-carbamoylbenzofuran-3-yl)-1,3-benzothiazole-2-carboxamide | N-[2-(aminocarbonyl)-1-benzofuran-3-yl]-1,3-benzothiazole-2-carboxamide | SMR000020707 | cid_2141383
Type:
Small organic molecule
Emp. Form.:
C17H11N3O3S
Mol. Mass.:
337.353
SMILES:
NC(=O)c1oc2ccccc2c1NC(=O)c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: