Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM40568
Substrate
n/a
Meas. Tech.
High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters
IC50
>25000±0 nM
Citation
 PubChem, PC High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM40568
Synonyms:
2-Imino-10-oxo-1-pyridin-3-ylmethyl-1,10-dihydro-2H-1,9,10a-triaza-anthracene-3-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide | 2-azanylidene-5-oxidanylidene-N-(oxolan-2-ylmethyl)-1-(pyridin-3-ylmethyl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-imino-5-keto-1-(3-pyridylmethyl)-N-(tetrahydrofurfuryl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-imino-5-oxo-N-(2-oxolanylmethyl)-1-(3-pyridinylmethyl)-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 2-imino-5-oxo-N-(oxolan-2-ylmethyl)-1-(pyridin-3-ylmethyl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS000072913 | SMR000013117 | cid_646508
Type:
Small organic molecule
Emp. Form.:
C23H22N6O3
Mol. Mass.:
430.4592
SMILES:
N=c1c(cc2c(nc3ccccn3c2=O)n1Cc1cccnc1)C(=O)NCC1CCCO1
Structure:
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