Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM40732
Substrate
n/a
Meas. Tech.
High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters
IC50
2821.2±370 nM
Citation
 PubChem, PC High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM40732
Synonyms:
(3E)-3-[(5E)-5-[[(N''E)-N''-[amino(nitramido)methylene]hydrazino]methylene]-2-furylidene]-6-keto-cyclohexa-1,4-diene-1-carboxylic acid | (3E)-3-[(5E)-5-[[(N'E)-N'-[amino(nitramido)methylene]hydrazino]methylene]-2-furylidene]-6-keto-cyclohexa-1,4-diene-1-carboxylic acid | (3Z)-3-[(5Z)-5-[[2-[amino(nitramido)methylidene]hydrazinyl]methylidene]-2-furanylidene]-6-oxo-1-cyclohexa-1,4-dienecarboxylic acid | (3Z)-3-[(5Z)-5-[[2-[amino(nitramido)methylidene]hydrazinyl]methylidene]furan-2-ylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid | (3Z)-3-[(5Z)-5-[[2-[azanyl(nitramido)methylidene]hydrazinyl]methylidene]furan-2-ylidene]-6-oxidanylidene-cyclohexa-1,4-diene-1-carboxylic acid | (3Z)-3-[(5Z)-5-[[N'-[amino(nitramido)methylene]hydrazino]methylene]-2-furylidene]-6-keto-cyclohexa-1,4-diene-1-carboxylic acid | 5-(5-{2-[amino(nitroimino)methyl]carbonohydrazonoyl}-2-furyl)-2-hydroxybenzoic acid | MLS000575572 | SMR000185710 | cid_11958908 | cid_5333267
Type:
Small organic molecule
Emp. Form.:
C13H11N5O6
Mol. Mass.:
333.2563
SMILES:
NC(N[N+]([O-])=O)=NNC=c1ccc(o1)=C1C=CC(=O)C(=C1)C(O)=O |w:6.6,8.7,14.21,c:16,20|
Structure:
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