Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM40754
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : FPR Dose Response Counterscreen Assay
Ki
>37400±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : FPR Dose Response Counterscreen Assay PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM40754
Synonyms:
N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl)-2-(4-methoxyphenyl)acetamide | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl)-2-(4-methoxyphenyl)ethanamide | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxyphenyl)-2-(4-methoxyphenyl)acetamide | N-[5-(2-imidazo[1,2-a]pyrimidinyl)-2-methoxyphenyl]-2-(4-methoxyphenyl)acetamide | UNM000003661901 | cid_7080289
Type:
Small organic molecule
Emp. Form.:
C22H20N4O3
Mol. Mass.:
388.4192
SMILES:
COc1ccc(CC(=O)Nc2cc(ccc2OC)-c2cn3cccnc3n2)cc1
Structure:
Search PDB for entries with ligand similarity: