Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40750
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
IC50
3600±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40750
Synonyms:
N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl)-2-methyl-propanamide | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl)-2-methyl-propionamide | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxyphenyl)-2-methylpropanamide | N-[5-(2-imidazo[1,2-a]pyrimidinyl)-2-methoxyphenyl]-2-methylpropanamide | UNM000003657701 | cid_6622773
Type:
Small organic molecule
Emp. Form.:
C17H18N4O2
Mol. Mass.:
310.3504
SMILES:
COc1ccc(cc1NC(=O)C(C)C)-c1cn2cccnc2n1
Structure:
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