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Target
Complement C1s subcomponent
Ligand
BDBM40795
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40795
Synonyms:
2-Biphenyl-4-yl-N-(2-morpholin-4-yl-ethyl)-acetamide | MLS000031311 | N-(2-morpholin-4-ylethyl)-2-(4-phenylphenyl)acetamide | N-(2-morpholin-4-ylethyl)-2-(4-phenylphenyl)ethanamide | N-(2-morpholinoethyl)-2-(4-phenylphenyl)acetamide | N-[2-(4-morpholinyl)ethyl]-2-(4-phenylphenyl)acetamide | SMR000013269 | cid_649839
Type:
Small organic molecule
Emp. Form.:
C20H24N2O2
Mol. Mass.:
324.4168
SMILES:
O=C(Cc1ccc(cc1)-c1ccccc1)NCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: