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Target
Complement C1s subcomponent
Ligand
BDBM32673
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
10100±1880 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM32673
Synonyms:
(4-ethyl-7-methyl-2-oxidanylidene-chromen-5-yl) furan-2-carboxylate | (4-ethyl-7-methyl-2-oxochromen-5-yl) furan-2-carboxylate | 2-furancarboxylic acid (4-ethyl-7-methyl-2-oxo-1-benzopyran-5-yl) ester | 4-ethyl-7-methyl-2-oxo-2H-chromen-5-yl 2-furoate | MLS000099547 | SMR000071303 | cid_1121645 | furan-2-carboxylic acid (4-ethyl-2-keto-7-methyl-chromen-5-yl) ester
Type:
Small organic molecule
Emp. Form.:
C17H14O5
Mol. Mass.:
298.2901
SMILES:
CCc1cc(=O)oc2cc(C)cc(OC(=O)c3ccco3)c12
Structure:
Search PDB for entries with ligand similarity: