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Target
Cathepsin B
Ligand
BDBM41096
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41096
Synonyms:
(2-morpholin-4-yl-2-oxidanylidene-ethyl) 4-azanyl-1,2,5-oxadiazole-3-carboxylate | (2-morpholin-4-yl-2-oxoethyl) 4-amino-1,2,5-oxadiazole-3-carboxylate | 4-Amino-furazan-3-carboxylic acid 2-morpholin-4-yl-2-oxo-ethyl ester | 4-amino-1,2,5-oxadiazole-3-carboxylic acid [2-(4-morpholinyl)-2-oxoethyl] ester | 4-aminofurazan-3-carboxylic acid (2-keto-2-morpholino-ethyl) ester | MLS000068291 | SMR000010122 | cid_651703
Type:
Small organic molecule
Emp. Form.:
C9H12N4O5
Mol. Mass.:
256.2154
SMILES:
Nc1nonc1C(=O)OCC(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: