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Target
Cathepsin B
Ligand
BDBM41097
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41097
Synonyms:
2-[(2-Benzotriazol-1-yl-acetyl)-pyridin-3-yl-amino]-N-(2-methoxy-ethyl)-2-(3-methoxy-phenyl)-acetamide | 2-[2-(benzotriazol-1-yl)ethanoyl-pyridin-3-yl-amino]-N-(2-methoxyethyl)-2-(3-methoxyphenyl)ethanamide | 2-[[2-(1-benzotriazolyl)-1-oxoethyl]-(3-pyridinyl)amino]-N-(2-methoxyethyl)-2-(3-methoxyphenyl)acetamide | 2-[[2-(benzotriazol-1-yl)acetyl]-(3-pyridyl)amino]-N-(2-methoxyethyl)-2-(3-methoxyphenyl)acetamide | 2-[[2-(benzotriazol-1-yl)acetyl]-pyridin-3-ylamino]-N-(2-methoxyethyl)-2-(3-methoxyphenyl)acetamide | MLS000032366 | SMR000005231 | cid_655872
Type:
Small organic molecule
Emp. Form.:
C25H26N6O4
Mol. Mass.:
474.5117
SMILES:
COCCNC(=O)C(N(C(=O)Cn1nnc2ccccc12)c1cccnc1)c1cccc(OC)c1
Structure:
Search PDB for entries with ligand similarity: