Reaction Details Report a problem with these data
Target
Cathepsin B
Ligand
BDBM41101
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
39986.8±9937.6 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41101
Synonyms:
MLS000027599 | SMR000039890 | [4-[(2-methoxyphenyl)iminomethyl]-2-phenyl-1,3-oxazol-5-yl] propanoate | cid_658964 | propanoic acid [4-[(2-methoxyphenyl)iminomethyl]-2-phenyl-5-oxazolyl] ester | propionic acid [4-[(2-methoxyphenyl)iminomethyl]-2-phenyl-oxazol-5-yl] ester
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4
Mol. Mass.:
350.3679
SMILES:
CCC(=O)Oc1oc(nc1\C=N\c1ccccc1OC)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: