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Target
Cathepsin B
Ligand
BDBM41108
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41108
Synonyms:
MLS000089550 | N-(3-chlorophenyl)-N-ethyl-2-(1-ethyl-2-oxidanylidene-quinolin-4-yl)oxy-ethanamide | N-(3-chlorophenyl)-N-ethyl-2-(1-ethyl-2-oxoquinolin-4-yl)oxyacetamide | N-(3-chlorophenyl)-N-ethyl-2-[(1-ethyl-2-keto-4-quinolyl)oxy]acetamide | N-(3-chlorophenyl)-N-ethyl-2-[(1-ethyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]acetamide | N-(3-chlorophenyl)-N-ethyl-2-[(1-ethyl-2-oxo-4-quinolinyl)oxy]acetamide | SMR000027898 | cid_3236055
Type:
Small organic molecule
Emp. Form.:
C21H21ClN2O3
Mol. Mass.:
384.856
SMILES:
CCN(C(=O)COc1cc(=O)n(CC)c2ccccc12)c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: