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Target
Cathepsin B
Ligand
BDBM41110
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41110
Synonyms:
MLS000084822 | N'-(6-methoxy-1,3-benzothiazol-2-yl)-N,N-dimethylimidoformamide | N'-(6-methoxy-1,3-benzothiazol-2-yl)-N,N-dimethyl-formamidine | N'-(6-methoxy-1,3-benzothiazol-2-yl)-N,N-dimethyl-methanimidamide | N'-(6-methoxy-1,3-benzothiazol-2-yl)-N,N-dimethylmethanimidamide | SMR000019168 | cid_380199
Type:
Small organic molecule
Emp. Form.:
C11H13N3OS
Mol. Mass.:
235.305
SMILES:
COc1ccc2nc(N=CN(C)C)sc2c1 |w:8.7|
Structure:
Search PDB for entries with ligand similarity: