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Target
Cathepsin B
Ligand
BDBM41113
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41113
Synonyms:
(1E)-N'-[(4-chlorophenyl)sulfonyl]ethanimidamide | MLS000087917 | N'-(4-chlorophenyl)sulfonylacetamidine | N'-(4-chlorophenyl)sulfonylethanimidamide | SMR000024235 | cid_6023689
Type:
Small organic molecule
Emp. Form.:
C8H9ClN2O2S
Mol. Mass.:
232.687
SMILES:
CC(=N)NS(=O)(=O)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: