Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM41159
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
733.213±464.437 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41159
Synonyms:
MLS000046447 | N-(3-azepan-1-ylpropyl)-3-[3-(4-chlorophenyl)-6-oxopyridazin-1(6H)-yl]propanamide | N-[3-(1-azepanyl)propyl]-3-[3-(4-chlorophenyl)-6-oxo-1-pyridazinyl]propanamide | N-[3-(azepan-1-yl)propyl]-3-[3-(4-chlorophenyl)-6-keto-pyridazin-1-yl]propionamide | N-[3-(azepan-1-yl)propyl]-3-[3-(4-chlorophenyl)-6-oxidanylidene-pyridazin-1-yl]propanamide | N-[3-(azepan-1-yl)propyl]-3-[3-(4-chlorophenyl)-6-oxopyridazin-1-yl]propanamide | SMR000032458 | cid_3240872
Type:
Small organic molecule
Emp. Form.:
C22H29ClN4O2
Mol. Mass.:
416.944
SMILES:
Clc1ccc(cc1)-c1ccc(=O)n(CCC(=O)NCCCN2CCCCCC2)n1
Structure:
Search PDB for entries with ligand similarity: