Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM40309
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
2368.47±273.165 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM40309
Synonyms:
MLS000046765 | N-(3-azepan-1-ylpropyl)-5-{[(2-fluorobenzyl)sulfonyl]methyl}-2-furamide | N-[3-(1-azepanyl)propyl]-5-[(2-fluorophenyl)methylsulfonylmethyl]-2-furancarboxamide | N-[3-(azepan-1-yl)propyl]-5-[(2-fluorobenzyl)sulfonylmethyl]-2-furamide | N-[3-(azepan-1-yl)propyl]-5-[(2-fluorophenyl)methylsulfonylmethyl]furan-2-carboxamide | SMR000032776 | cid_3241115
Type:
Small organic molecule
Emp. Form.:
C22H29FN2O4S
Mol. Mass.:
436.54
SMILES:
Fc1ccccc1CS(=O)(=O)Cc1ccc(o1)C(=O)NCCCN1CCCCCC1
Structure:
Search PDB for entries with ligand similarity: