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Target
Procathepsin L
Ligand
BDBM41170
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41170
Synonyms:
MLS000086422 | N-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-[4-(2-furoyl)piperazino]acetamide | N-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide | N-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]ethanamide | N-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]acetamide | N-1,3-benzodioxol-5-yl-2-(4-chlorophenyl)-2-[4-(2-furoyl)piperazin-1-yl]acetamide | SMR000021924 | cid_3245657
Type:
Small organic molecule
Emp. Form.:
C24H22ClN3O5
Mol. Mass.:
467.902
SMILES:
Clc1ccc(cc1)C(N1CCN(CC1)C(=O)c1ccco1)C(=O)Nc1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: