Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41322
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41322
Synonyms:
2-[(6-benzyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)sulfanyl]-N-(furan-2-ylmethyl)acetamide | 2-[(6-benzyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)thio]-N-(2-furfuryl)acetamide | 2-[(6-benzyl-5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)thio]-N-(2-furylmethyl)acetamide | 2-[[5,7-dimethyl-6-(phenylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]sulfanyl]-N-(furan-2-ylmethyl)ethanamide | 2-[[5,7-dimethyl-6-(phenylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]thio]-N-(2-furanylmethyl)acetamide | MLS000086687 | SMR000022727 | cid_3241666
Type:
Small organic molecule
Emp. Form.:
C21H21N5O2S
Mol. Mass.:
407.489
SMILES:
Cc1nc2nc(SCC(=O)NCc3ccco3)nn2c(C)c1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: