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Target
Cathepsin S
Ligand
BDBM41327
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41327
Synonyms:
4-(1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester | 4-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester | MLS000093210 | SMR000028832 | cid_3243791 | ethyl 4-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | ethyl 4-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylcarbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate | ethyl 4-(1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H24N2O5
Mol. Mass.:
336.3829
SMILES:
CCOC(=O)c1[nH]c(C)c(C(=O)N2CCC3(CC2)OCCO3)c1C
Structure:
Search PDB for entries with ligand similarity: