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Target
Cathepsin S
Ligand
BDBM41346
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41346
Synonyms:
2-[(2,4-dichlorophenoxy)methyl]-5-(2,6-dimethyl-4-morpholinyl)-1,3-oxazole-4-carbonitrile | 2-[(2,4-dichlorophenoxy)methyl]-5-(2,6-dimethyl-4-morpholinyl)-4-oxazolecarbonitrile | 2-[(2,4-dichlorophenoxy)methyl]-5-(2,6-dimethylmorpholin-4-yl)-1,3-oxazole-4-carbonitrile | 2-[(2,4-dichlorophenoxy)methyl]-5-(2,6-dimethylmorpholino)oxazole-4-carbonitrile | 2-[[2,4-bis(chloranyl)phenoxy]methyl]-5-(2,6-dimethylmorpholin-4-yl)-1,3-oxazole-4-carbonitrile | MLS000065135 | SMR000078603 | cid_2963508
Type:
Small organic molecule
Emp. Form.:
C17H17Cl2N3O3
Mol. Mass.:
382.241
SMILES:
CC1CN(CC(C)O1)c1oc(COc2ccc(Cl)cc2Cl)nc1C#N
Structure:
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