Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41353
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41353
Synonyms:
MLS000065709 | N-(5-methyl-1,3,4-thiadiazol-2-yl)-5-propyl-3-thiophenecarboxamide | N-(5-methyl-1,3,4-thiadiazol-2-yl)-5-propyl-thiophene-3-carboxamide | N-(5-methyl-1,3,4-thiadiazol-2-yl)-5-propylthiophene-3-carboxamide | SMR000080372 | cid_1245519
Type:
Small organic molecule
Emp. Form.:
C11H13N3OS2
Mol. Mass.:
267.37
SMILES:
CCCc1cc(cs1)C(=O)Nc1nnc(C)s1
Structure:
Search PDB for entries with ligand similarity: