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Target
Cathepsin S
Ligand
BDBM35520
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
3615.18±255.356 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM35520
Synonyms:
4-(4-morpholinyl)-6-(1-piperidinyl)-1,3,5-triazine-2-carbonitrile | 4-morpholin-4-yl-6-piperidin-1-yl-1,3,5-triazine-2-carbonitrile | 4-morpholino-6-piperidino-s-triazine-2-carbonitrile | MLS000099932 | SMR000081092 | cid_729563
Type:
Small organic molecule
Emp. Form.:
C13H18N6O
Mol. Mass.:
274.3216
SMILES:
N#Cc1nc(nc(n1)N1CCOCC1)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: