Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM41386
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41386
Synonyms:
5-cyano-4-(2-methoxyphenyl)-2-methyl-6-(2-oxidanylidene-2-pyrrolidin-1-yl-ethyl)sulfanyl-pyridine-3-carboxamide | 5-cyano-4-(2-methoxyphenyl)-2-methyl-6-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanylpyridine-3-carboxamide | 5-cyano-4-(2-methoxyphenyl)-2-methyl-6-[[2-oxo-2-(1-pyrrolidinyl)ethyl]thio]-3-pyridinecarboxamide | 5-cyano-6-[(2-keto-2-pyrrolidino-ethyl)thio]-4-(2-methoxyphenyl)-2-methyl-nicotinamide | MLS000098127 | SMR000061200 | cid_2998610
Type:
Small organic molecule
Emp. Form.:
C21H22N4O3S
Mol. Mass.:
410.489
SMILES:
COc1ccccc1-c1c(C#N)c(SCC(=O)N2CCCC2)nc(C)c1C(N)=O |(11.91,4.65,;10.58,3.88,;9.24,4.65,;9.24,6.19,;7.91,6.96,;6.57,6.19,;6.57,4.65,;7.91,3.88,;7.91,2.34,;9.24,1.57,;10.58,2.34,;11.91,3.11,;9.24,.03,;10.58,-.74,;10.58,-2.28,;11.91,-3.05,;13.24,-2.28,;11.91,-4.59,;13.16,-5.5,;12.68,-6.96,;11.14,-6.96,;10.66,-5.5,;7.91,-.74,;6.57,.03,;5.24,-.74,;6.57,1.57,;5.24,2.34,;3.91,1.57,;5.24,3.88,)|
Structure:
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