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Target
Cathepsin G
Ligand
BDBM41387
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
3857.13±159.576 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41387
Synonyms:
5-amino-1-[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoyl]pyrazole-4-carbonitrile | 5-amino-1-[4-[[(4-methyl-1,2,4-triazol-3-yl)thio]methyl]benzoyl]pyrazole-4-carbonitrile | 5-amino-1-[[4-[[(4-methyl-1,2,4-triazol-3-yl)thio]methyl]phenyl]-oxomethyl]-4-pyrazolecarbonitrile | 5-azanyl-1-[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]carbonyl-pyrazole-4-carbonitrile | MLS000057838 | SMR000063201 | cid_2084089
Type:
Small organic molecule
Emp. Form.:
C15H13N7OS
Mol. Mass.:
339.375
SMILES:
Cn1cnnc1SCc1ccc(cc1)C(=O)n1ncc(C#N)c1N
Structure:
Search PDB for entries with ligand similarity: