Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM40382
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
3612.03±205.023 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM40382
Synonyms:
1-(4,5,6,7-tetrahydro-1-benzothien-3-ylcarbonyl)-1H-pyrazole | 1-pyrazolyl(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone | MLS000065702 | SMR000080360 | cid_1245419 | pyrazol-1-yl(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone | pyrazol-1-yl(4,5,6,7-tetrahydrobenzothiophen-3-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C12H12N2OS
Mol. Mass.:
232.301
SMILES:
O=C(c1csc2CCCCc12)n1cccn1
Structure:
Search PDB for entries with ligand similarity: