Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41605
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor
IC50
8004±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41605
Synonyms:
3-(1-Methyl-1H-benzoimidazol-2-yl)-1-(3-phenyl-propyl)-1H-pyrrolo[2,3-b]quinoxalin-2-ylamine | 3-(1-methyl-2-benzimidazolyl)-1-(3-phenylpropyl)-2-pyrrolo[3,2-b]quinoxalinamine | 3-(1-methylbenzimidazol-2-yl)-1-(3-phenylpropyl)pyrrolo[3,2-b]quinoxalin-2-amine | MLS000559002 | SMR000149318 | [3-(1-methylbenzimidazol-2-yl)-1-(3-phenylpropyl)pyrrolo[3,2-b]quinoxalin-2-yl]amine | cid_4971561
Type:
Small organic molecule
Emp. Form.:
C27H24N6
Mol. Mass.:
432.5197
SMILES:
Cn1c(nc2ccccc12)-c1c(N)n(CCCc2ccccc2)c2nc3ccccc3nc12 |(8.02,4.62,;9.56,4.62,;10.46,3.38,;11.91,3.85,;11.92,5.38,;13.07,6.41,;12.75,7.91,;11.28,8.39,;10.14,7.36,;10.46,5.86,;9.98,1.92,;10.88,.68,;12.42,.68,;9.98,-.56,;10.46,-2.03,;9.43,-3.17,;9.91,-4.64,;8.88,-5.78,;7.37,-5.47,;6.34,-6.61,;6.82,-8.08,;8.33,-8.39,;9.35,-7.25,;8.52,-.09,;7.19,-.86,;5.85,-.09,;4.48,-.92,;3.08,-.13,;3.08,1.48,;4.48,2.27,;5.85,1.45,;7.19,2.22,;8.52,1.45,)|
Structure:
Search PDB for entries with ligand similarity: