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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM34428
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
EC50
>50000±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM34428
Synonyms:
(3-hydroxyphenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione | (3-hydroxyphenyl)-[4-(phenylmethyl)piperazin-1-yl]methanethione | (4-benzylpiperazin-1-yl)-(3-hydroxyphenyl)methanethione | (4-benzylpiperazino)-(3-hydroxyphenyl)methanethione | 3-[(4-benzyl-1-piperazinyl)carbonothioyl]phenol | MLS000050509 | SMR000076439 | cid_2204910
Type:
Small organic molecule
Emp. Form.:
C18H20N2OS
Mol. Mass.:
312.429
SMILES:
Oc1cccc(c1)C(=S)N1CCN(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: