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Target
Beta-lactamase
Ligand
BDBM41852
Substrate
n/a
Meas. Tech.
Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)
Ki
17000±n/a nM
Citation
 PubChem, PC Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent) PubChem Bioassay (2008)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM41852
Synonyms:
2-[(1R)-1-carboxy-2-(2,4-dimethylphenyl)ethyl]-1,3-diketo-isoindoline-5-carboxylic acid | 2-[(1R)-1-carboxy-2-(2,4-dimethylphenyl)ethyl]-1,3-dioxo-5-isoindolecarboxylic acid | 2-[(1R)-1-carboxy-2-(2,4-dimethylphenyl)ethyl]-1,3-dioxoisoindole-5-carboxylic acid | 2-[(2R)-3-(2,4-dimethylphenyl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]-1,3-bis(oxidanylidene)isoindole-5-carboxylic acid | NCGC00161794-01 | cid_16752644
Type:
Small organic molecule
Emp. Form.:
C20H17NO6
Mol. Mass.:
367.3521
SMILES:
Cc1ccc(C[C@@H](N2C(=O)c3ccc(cc3C2=O)C(O)=O)C(O)=O)c(C)c1
Structure:
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