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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM41873
Substrate
n/a
Meas. Tech.
Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase
IC50
2060±n/a nM
Citation
 PubChem, PC Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase PubChem Bioassay (2009)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM41873
Synonyms:
2-[5-(2-furanyl)-1H-1,2,4-triazol-3-yl]-1,3-dioxo-5-isoindolecarboxylic acid | 2-[5-(2-furyl)-1H-1,2,4-triazol-3-yl]-1,3-diketo-isoindoline-5-carboxylic acid | 2-[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]-1,3-bis(oxidanylidene)isoindole-5-carboxylic acid | 2-[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]-1,3-dioxoisoindole-5-carboxylic acid | MLS-0146260.0001 | cid_2971779
Type:
Small organic molecule
Emp. Form.:
C15H8N4O5
Mol. Mass.:
324.2478
SMILES:
OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1nnc([nH]1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: